Vol. 7, Issue 2, Part A (2025)

The significance of glucose as a ruminant energy source is explored in this article, with particular attention paid to the body's absorption and metabolism of the substance. It emphasizes the function of glucose transporters in the kidney, liver, and small intestine, in addition to the influence of dietary and hormonal variables on glucose metabolism. The hormonal control of glucose metabolism in ruminants is covered, with particular attention paid to the functions of insulin, Growth Hormone (GH), and glucose transporters. It also emphasizes how these hormones affect the uptake and utilization of glucose in different tissues, such as the kidneys, liver, and muscle cells. The effect of GH and GH-Releasing Factor (GHRF) on the expression of glucose transporters and glucose partitioning in ruminants is also examined in this review. It also explores the peripheral tissues' sensitivity to insulin and how it relates to animal health. The importance of dietary components like cellulose and cereal grains in supplying metabolizable energy for rumen microbial fermentation is emphasized in this review. It emphasizes the relevance of the rumen's ability to digest starch, ferment volatile fatty acids, and provide glucose for several physiological processes. It also examines the connection between rumen digestion and starch intake, highlighting the crucial role that dietary factors play in ruminant animals' glucose metabolism.