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International Journal of Bioscience and Biochemistry

Vol. 6, Issue 1, Part B (2024)

Occurrence and risk factors associated with antimicrobial resistance of E. coli

Author(s):

Ephrem Shimelis and Hika Waktole

Abstract:

Antimicrobial resistance is current world wide One Health issues in the areas of human, animal, and environmental fields due to the extensive use and misuse of antimicrobials in the human and animal fields as for growth promotion, prophylaxis and therapeutics. The transfer of antibiotic resistance E. coli from animals to humans is of concern in recent times. The b-lactam antibiotics have been used successfully to treat infections caused by pathogenic E. coli. However, currently, the utility of b-lactams is being challenged severely by a large number of hydrolytic enzymes the b-lactamases expressed by bacteria. The b-lactam antibiotics have been used successfully to treat infections caused by pathogenic E. coli. However, currently, the utility of b-lactams is being challenged severely by a large number of hydrolytic enzymes the b-lactamases expressed by bacteria. The handling and consumption of poultry or poultry products is the risk factors repeatedly associated with the transmission of bacterial pathogens to the human population. The control and prevention of such treats require the knowledge, attitude and practices of using antimicrobials in poultry farm as recommended by different scholars. Successful management of infections caused by such resistant strains requires an understanding of the diversity of b-lactamases, their unambiguous detection, and molecular mechanisms underlying their expression and spread with regard to the most relevant information about individual bacterial species. Properly using the antibiotics as its recommended time intervals and dosages, using specific spectrum rather than broad spectrum, educe the using of antibiotic as prophylaxis and growth promoters in Animal feeds and training of farmers and other community on the public health importance and risk factors associated with the antimicrobial resistant bacterial infections. Asterisk.

Pages: 111-115  |  87 Views  33 Downloads


International Journal of Bioscience and Biochemistry
How to cite this article:
Ephrem Shimelis and Hika Waktole. Occurrence and risk factors associated with antimicrobial resistance of E. coli. Int. J. Biosci. Biochem. 2024;6(1):111-115. DOI: 10.33545/26646536.2024.v6.i1b.71
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